The charismatic and self-confident man, Karel Král, is the editor-in-chief of men's magazine. Although a chauvinistic type, he is very popular with women. However, he struggles in his personal life. He frequently argues with his ex-wife over their 17 year-old daughter Julie, who despises his new way of life. Then the consequences of his behavior catch up with him. He loses his job, and the editor-in-chief position is given to a young and beautiful woman. But his bad luck does not end there. After another fight with his ex-wife and daughter, and a woman driver crashing into his car, Karel and his best friend Cestmír have an evening of binge drinking. During the wild night, he expresses a wish to be a woman. When he wakes up the next morning he discovers that his wish has been granted.

Irena Kopáčová, a relationship psychologist, hits rock bottom when her practice lease is terminated and she discovers her partner’s infidelity. After drunkenly visiting a soothsayer and wishing to be a man, she wakes up in a male body and must navigate life from an entirely new perspective, struggling to convince others of her true identity.